CoQ10 benefits in type 2 diabetes and in inflammation


CoQ10 improves factors in diabetic kidney disease

In this study, 50 people with diabetic kidney disease took a placebo or 100 mg of CoQ10 per day. After 12 weeks, doctors discovered several benefits.

For those taking CoQ10, insulin levels decreased by 3.4 mass- international units per milliliter of blood (µIU/mL), while increasing 0.8 for placebo. Also for CoQ10, insulin resistance and long-term average blood sugar levels decreased while increasing for placebo.

Doctors also found fewer signs of oxidative stress in the CoQ10 group, but more signs of oxidation for placebo. In one of the most important findings, levels of a blood vessel-damaging protein that forms when blood sugar is chronically elevated—a factor in diabetic kidney disease—were lower for CoQ10 while increasing for placebo.

CoQ10 lowers chronic inflammation

Cells in the body make coenzymeQ10, a prime factor in creating cellular energy. Certain tissues in the body, such as heart, kidney, liver, and skeletal muscle, have especially high energy requirements, and need lots of CoQ10. The aim of this review of seven CoQ10 studies was to measure the effects of taking CoQ10 supplements on C-reactive protein (CRP), a sign of systemic inflammation.

Overall, CoQ10 moderately lowered CRP levels. In addition, doctors also found that CoQ10 significantly lowered levels of another inflammatory factor, interleukin-6 (IL-6), which promotes CRP.

Discussing the findings, doctors said that CoQ10 has a moderately favorable effect on lowering CRP, a significant effect on lowering IL-6, and that taking CoQ10 supplements likely reduces mild chronic inflammation.

Reference: Journal of the American College of
Nutrition; November, 2017, Published Online
Natural Insights for Well Being April 2018

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